The conference, on reducing inequities in reproductive, maternal and child health in the Latin America and the Caribbean region, will provide a regional forum to celebrate successes, review trends in reproductive, maternal, neonatal, child, and adolescent health in the Region of the Americas, and to identify key interventions and strategic shifts needed to reduce persisting inequalities in health. The meeting will help galvanize regional efforts to accelerate achievement of Millennium Development Goals (MDGs) 4 and 5 by 2015, and contribute to development of the post-MDG development agenda. The meeting will also formally link the Americas to the global “A Promise Renewed” movement to eliminate preventable child and maternal deaths by 2035.